Profiling the Response of Human Hair Follicles to Ultraviolet Radiation
January 2009
in “
Journal of Investigative Dermatology
”
UVB radiation hair shaft elongation catagen phase hair matrix keratinocytes apoptotic cell death necrotic cell death mitochondrial DNA damage genomic DNA damage follicular melanogenesis ACTH immunoreactivity transforming growth factor-ß₂ mast cells degranulation CD117 immunoreactivity hair growth cycle melanin synthesis cell proliferation cell death markers UVB hair growth hair cycle melanin cell death
Studysummary In this study, UVB irradiation of organ-cultured human anagen hair follicles in vitro reduced hair elongation and increased cell death, affecting hair growth and regulatory processes.
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