Corticotropin-Releasing Hormone and the Skin

    January 2006 in “ Frontiers in bioscience ”
    Andrzej Słomiński
    Studysummary This review discusses the role of corticotropin-releasing hormone in human skin, focusing on its regulation, receptors, and functions, and highlights parallels with the hypothalamo-pituitary-adrenal axis; it reports no new research findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Neuroimmunology of Stress: Skin Takes Center Stage Journal of Investigative Dermatology · 2006
    2. Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of Alpha-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells Endocrinology · 2005
    3. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    4. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    5. Androgen Action on Human Skin – From Basic Research to Clinical Significance Experimental dermatology · 2004
    6. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004
    7. Corticotropin-Releasing Hormone: An Autocrine Hormone That Promotes Lipogenesis in Human Sebocytes Proceedings of the National Academy of Sciences · 2002
    8. The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle Annals of the New York Academy of Sciences · 1999