54 citations
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January 2016 in “Cell reports” This study found that different epidermal stem cell populations contribute to the formation of various skin tumors and new hair follicles following β-catenin activation in the adult epidermis.
25 citations
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March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that while VDR is crucial for maintaining hair follicles in mice, their degeneration may be linked to impaired cell migration during hair growth phases rather than stem cell loss.
2 citations
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August 2012 in “Cell Stem Cell” This study used two-photon microscopy to reveal that the dermal papilla is crucial for hair follicle regeneration and cannot be replaced by neighboring cells, providing new insights into stem cell behavior.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported significant transcriptomic changes in keratinocyte and immune cell populations in a mouse model with EGFR-deficient epidermis, suggesting possible targets for mitigating adverse skin events in EGFR-targeted cancer therapy.
91 citations
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June 2011 in “The EMBO Journal” This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.