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New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

12 citations, April 2020 in “British Journal of Dermatology”

Caffeine may help reduce stress-induced hair loss.

research Corticotropin-Releasing Hormone and the Skin

137 citations, January 2006 in “Frontiers in bioscience”

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

research Gene Polymorphisms and Serum Levels of BDNF and CRH in Vitiligo Patients

July 2022 in “PLOS ONE”

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

research Neuroimmunology of Stress: Skin Takes Center Stage

375 citations, July 2006 in “Journal of Investigative Dermatology”

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

research Pruritus, Allergy and Autoimmunity: Paving the Way for an Integrated Understanding of Psychodermatological Diseases

4 citations, September 2021 in “Frontiers in allergy”

The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.

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community How does hair loss and recovery work?

in Chat 12 upvotes 3 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.