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In this study, researchers found that caffeine can counteract stress-induced damage in ex vivo human androgenetic alopecia hair follicles, suggesting it may help prevent stress-related hair loss.

In this study, CRH receptor antagonists from Pulsatilla chinensis reversed stress hormone-induced changes in hair follicles and dermal papilla cells in a lab setting, suggesting potential pharmaceutical and cosmetic applications for treating stress-related hair loss.

This study found that patients with alopecia areata exhibited increased CRHR1 expression on circulating monocytes compared to controls, suggesting that stress-related factors like CRH and CRHR1 may contribute to the development and progression of the condition, particularly in chronic cases and those with larger lesions.

This report describes a rare case of ectopic adrenocorticotropic hormone syndrome caused by a pheochromocytoma that unusually co-expresses both ACTH and corticotropin-releasing hormone.

In this study, significant associations were observed between specific genetic polymorphisms in BDNF and CRH-R1 and the occurrence of vitiligo, along with differing serum levels of neurotransmitters between vitiligo patients and healthy controls.