This article discusses recent findings on hairgraying involving melanocyte stem cell maintenance and key regulatory molecules, and reports no new experimental results.
67 citations
,
August 2013 in “International Journal of Cosmetic Science”
This review discusses the role of oxidative stress in hairgreying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
62 citations
,
December 1941 in “Experimental biology and medicine”
In this study, phenylthiocarbamide intake was associated with hairgraying in rats, while switching to tap water led some rats to regain their original fur color, suggesting dietary factors influence pigmentation.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
This review examines the pathogenesis of premature hairgraying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.
This study found that compromised antioxidant activity in gray hair follicles affects both mature melanocytes and their immature precursors, linked to down-regulation of melanogenesis-related genes.
ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.
Catalase is discussed as a potential treatment for delaying or reversing grey hair, but no reliable medicine currently exists. Other mentioned treatments include Imatinib, senolytics like Quercetin and Fisetin, He Shou Wu, Argan oil, and reishi mushroom extract, though their effectiveness varies.
A 20-year-old male experienced bald spots and used minoxidil, which led to hair regrowth but also premature graying. He seeks advice on reversing graying through diet or supplements like catalase, while another user suggests vitamin D3 and sesame for hair color.
OP is exploring ways to stop or reverse greyinghair, using NAC and considering PABA supplements. Some users suggest hair dye, black strap molasses, and copper as potential solutions.
The user has accepted their hair loss and uses finasteride and minoxidil, with past use of RU58841 and dutasteride. They seek advice on supplements to slow down grayinghair.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.