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research Hydroxyl Radical Mediates Cisplatin-Induced Apoptosis in Human Hair Follicle Dermal Papilla Cells and Keratinocytes Through Bcl-2-Dependent Mechanism

52 citations , May 2011 in “APOPTOSIS”

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy

February 2023 in “Materials today bio”

The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.

research Apoptosis in Human Skin Development: Morphogenesis, Periderm, and Stem Cells

253 citations , March 1994 in “Developmental dynamics”

Apoptosis is essential for human skin development and forming a functional epidermis.

research Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress

67 citations , August 2013 in “International Journal of Cosmetic Science”

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

research P53 Involvement in the Control of Murine Hair Follicle Regression

71 citations , June 2001 in “American Journal of Pathology”

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

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community The end of balding: We may have just found the secret to hair regrowth

in Technology 676 upvotes 6 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.