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Glossary Pigment Production

biological process where cells create color-giving substances

Pigment production refers to the biological process by which cells create pigments, such as melanin, that give color to skin, hair, and eyes. In humans, melanocytes are the specialized cells responsible for producing melanin, which helps protect against UV radiation and determines variations in skin and hair color.

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Research

5 / 1000+ results

research Transgneic Endothelin 3 Regulates Murine Pigment Production and Coat Color

October 2017

This study found that transgenic expression of Endothelin 3 in mice can maintain a dark pigmentation phenotype independently of Mc1r signaling by regulating melanogenic genes.

research Age-Related Hair Pigment Loss

20 citations , January 2015 in “Current problems in dermatology”

This paper reviews recent research on hair graying, suggesting that an imbalance in oxidative stress handling may affect melanocyte stem cells and melanin production with age, and calls for exploring strategies to prolong melanin production.

research Skin melanocytes: biology and development

401 citations , January 2013 in “Postepy Dermatologii I Alergologii”

This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.

research Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging

152 citations , December 2003 in “Micron”

This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.

research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation

115 citations , August 2008 in “The Journal of Clinical Endocrinology & Metabolism”

In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.

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Community Join

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community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community Stopped on fin, diffuse thinner, white hairs meaning

in Finasteride/Dutasteride 5 upvotes 1 month ago

The user stopped using finasteride and noticed diffuse thinning and white hairs on the crown, considering restarting finasteride and adding minoxidil. White hairs are miniaturized follicles that may regain pigment and thickness with treatment, and it's suggested to wait 12 months before considering a hair transplant.

community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community The Role of Astaxanthin as a Nutraceutical in Health, Age-Related Conditions and Hair Loss

3 upvotes 3 years ago

Astaxanthin (ASX) is highlighted as a promising supplement for treating hair loss due to its antioxidant properties. It may help with inflammation and oxidative stress, which are linked to hair loss and aging.

community Finally, some real breakthroughs. A comparison of the two leading baldness treatments: PP405 versus ABS-201

106 upvotes 11 months ago

PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.

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Learn

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learn Stem Cell Factor

learn Scalp Micropigmentation

What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Are the pigments used in scalp micropigmentation safe? Providers describe SMP pigments as safe, medical-grade and made for the scalp, but those are supplier and clinic descriptions rather than regulatory approvals: no colour additive is approved for injection into the skin, and allergic reactions to tattoo pigment are documented.

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