TLDR Keratin hydrogel from human hair is a promising biocompatible material for soft tissue fillers.
The study investigated the feasibility of using keratin hydrogels, extracted from human hair, as filler materials for soft tissue. The keratin was extracted using a modified reduction method, maintaining its high molecular weight and self-assembly ability. The injectable keratin hydrogel demonstrated controlled water absorption up to 850%, good biocompatibility, and promoted angiogenesis and cell proliferation in subcutaneous injections in Sprague Dawley rats. These findings suggested that keratin hydrogels have promising applications in soft tissue filler materials.
140 citations,
August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
99 citations,
June 2011 in “Journal of biomedical materials research. Part A” Keratin hydrogels can slowly release effective ciprofloxacin to prevent infections.
517 citations,
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309 citations,
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30 citations,
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June 2019 in “The Egyptian Journal of Histology” Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.
2 citations,
June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
140 citations,
August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
