Alkylation of Human Hair Keratin for Tunable Hydrogel Erosion and Drug Delivery in Tissue Engineering Applications

    September 2015 in “ Acta biomaterialia ”
    Sola Han, Trevor R. Ham, Sharjil Haque … Justin M. Saul
    Studysummary This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on europepmc.org →
    Discuss this study in the Community →

    Research cited in this study 7

    1. A Human Hair Keratin Hydrogel Scaffold Enhances Median Nerve Regeneration in Nonhuman Primates: An Electrophysiological and Histological Study Tissue Engineering Part A · 2013
    2. Hemostatic Properties and the Role of Cell Receptor Recognition in Human Hair Keratin Protein Hydrogels Biomaterials · 2013
    3. Structure–Property Relationships of Meta-Kerateine Biomaterials Derived from Human Hair Acta biomaterialia · 2011
    4. Mechanical and Biological Properties of Keratose Biomaterials Biomaterials · 2011
    5. Keratin Hydrogels Support the Sustained Release of Bioactive Ciprofloxacin Journal of biomedical materials research. Part A · 2011
    6. Preparation of Scaffolds from Human Hair Proteins for Tissue-Engineering Applications Biomedical Materials · 2008
    7. The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves Biomaterials · 2007

    Related research 1

    1. Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins Advances in experimental medicine and biology · 2018