Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss

    Gorana Kuka Epstein, John H. Epstein
    Image of study
    TLDR Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
    The document from 2018 reviews the use of mesenchymal stem cells (MSCs) and stromal vascular fraction (SVF) for treating hair loss, highlighting adipose-derived stromal cells (ADSCs) as a promising source due to their accessibility. It references several studies, including one with 22 patients showing a mean increase in hair count, another with 21 patients reporting increased hair count after 3 months, and a retrospective study of 27 patients with female pattern hair loss showing increased hair density and thickness. A study with 9 patients suggested SVF with autologous adipose tissue is a safe and promising treatment, and case studies on alopecia areata and scleroderma-induced alopecia showed hair regrowth with fat injections. Additionally, a study with 23 patients treated with isolated stem cells from human follicles indicated improvement. The STYLE trial with 71 subjects showed an increase of 29 terminal hairs per square centimeter at 24 weeks. The authors conclude that adipose tissue has regenerative effects and potential for hair regeneration, but more research is needed to establish definitive protocols and effectiveness.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 13 results

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  301 upvotes 11 months ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

      in Progress Pictures  26 upvotes 8 months ago
      A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

    Related Research

    2 / 2 results