TLDR Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
In the 2017 review, adipose-derived stromal cells (ADSCs) were presented as a promising cell source for regenerative medicine due to their ease of isolation, high cell yield, and low sampling risk compared to other stem cells like those from bone marrow. ADSCs have been used in treating a variety of diseases, including hair loss, and have shown immune modulation, anti-ulcer, and anti-inflammatory properties. They are generally considered safe, with clinical trials reporting no severe adverse effects, although there is concern about their potential to promote cancer growth in cosmetic reconstructive surgery. The review calls for further research to fully assess the safety and efficacy of ADSCs in disease treatment, despite their demonstrated therapeutic potential.
Cited in this study
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132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
37 citations
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May 2016 in “Scientific Reports” Combining skin cells with fat-derived stem cells can improve hair growth.
53 citations
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April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
9 citations
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January 2016 in “PubMed” Stem cell therapy could be a promising alternative for hair regrowth with fewer side effects.
8 citations
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January 2016 in “Journal of Veterinary Medical Science” Lab-made tissues from dog fat stem cells can help grow hair by releasing a growth factor.
83 citations
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June 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
499 citations
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September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
134 citations
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January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.