Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges

    September 2023 in “ Stem cell research & therapy ”
    Yaping Wang, Tingting Gao, Bin Wang
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    TLDR Mesenchymal stem cells could help treat aging-related diseases better than current methods.
    The document reviews the application of mesenchymal stem cells (MSCs) in combating cellular senescence and addressing clinical challenges. MSCs show promise in treating age-related diseases like Alzheimer's, Parkinson's, cardiovascular diseases, osteoporosis, and hair loss due to their regenerative properties, ability to modulate immune responses, and reduce oxidative stress. Studies indicate MSCs can promote hair follicle regeneration, improve skin conditions, and enhance bone formation. However, challenges such as ensuring safety, efficacy, and long-term stability of MSC-based treatments remain, necessitating further research and clinical trials.
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