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    GlossaryCellular Senescence (senescence)

    state where cells permanently stop dividing but remain metabolically active

    Cellular senescence is a state in which cells stop dividing and enter a permanent state of growth arrest without dying. This process is a natural part of aging and acts as a defense mechanism against cancer, as it prevents damaged cells from proliferating. However, the accumulation of senescent cells over time can contribute to tissue dysfunction and age-related diseases.

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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  737 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Update on hair, will be posting monthly! Nov 8 – Jan 14

      in Progress Pictures  334 upvotes 1 year ago
      A user's progress with treating their hair loss, including using finasteride, minoxidil, retinoic acid, dermapenning twice weekly and ket 2% shampoo two to three times per week. Other users offered advice such as not derma penning too often or shaving the area bald for a couple of months.

      community Pyrilutamide update: three months

      in Update  33 upvotes 1 year ago
      A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.