Search
for

    Glossary Telomere Shortening

    gradual reduction of protective chromosome ends during cell division

    Telomere shortening refers to the gradual reduction in the length of telomeres, which are protective caps at the ends of chromosomes. Each time a cell divides, its telomeres become slightly shorter, eventually leading to cellular aging and dysfunction when they become critically short. This process is also known as telomere attrition and is a key factor in aging and age-related diseases.

    Related Terms

    Research 10 of 409

    1. Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita Science Advances · 2025 · 3 citations
    2. Local Artemis dysfunction may be one molecular mechanism for androgenetic alopecia via telomere shortening Medical Hypotheses · 2012
    3. Replicative stress, stem cells and aging Mechanisms of Ageing and Development · 2008 · 70 citations
    4. Do Changes in Chromosomes Cause Aging? Cell · 1996 · 50 citations
    5. Stem cells and aberrant signaling of molecular systems in skin aging Ageing Research Reviews · 2014 · 25 citations
    6. Normal and Aging Hair Biology and Structure ‘Aging and Hair' Current problems in dermatology · 2015 · 20 citations
    7. Causality of Aging Hallmarks Aging and Disease · 2025 · 1 citations
    8. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022 · 1 citations
    9. Le vieillissement de la peau et du follicule pileux : de la caractérisation clinique à l'étude fonctionnelle Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) · 2015 · 1 citations
    10. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →