Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging

    November 2014 in “ Ageing Research Reviews ”
    Yan Peng, Ming Xuan, Victor Leung, Biao Cheng
    Studysummary This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 13

    1. Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells Nature communications · 2014
    2. Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    3. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    4. Telocytes in Human Skin – Are They Involved in Skin Regeneration? Journal of Cellular and Molecular Medicine · 2012
    5. The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles Differentiation · 2009
    6. Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate Development · 2008
    7. Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    8. Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes Molecular and Cellular Biology · 2006
    9. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006
    10. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005
    11. The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit Journal of Investigative Dermatology Symposium Proceedings · 2003
    12. Skin Aging and Menopause: Implications for Treatment American Journal of Clinical Dermatology · 2003
    13. Hormone Replacement Therapy and the Skin Maturitas · 2000