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research A Mouse Model for the Basal Transcription and DNA Repair Syndrome Trichothiodystrophy

188 citations, June 1998 in “Molecular cell”

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

research Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging

25 citations, November 2014 in “Ageing Research Reviews”

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth

10 citations, May 2012 in “PloS one”

Low ERCC3 gene activity is linked to non-pigmented hair growth.

research Pathology of Mouse Models of Accelerated Aging

81 citations, February 2016 in “Veterinary pathology”

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

research Signaling Pathways in Hair Aging

November 2023 in “Frontiers in cell and developmental biology”

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 668 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community On Minoxidil once a day/microneedling once a week

in Progress Pictures 137 upvotes 1 year ago

User started minoxidil and microneedling for hair growth and saw amazing results, but recently experienced hair thinning again. Others suggest adding finasteride, but user is hesitant and has difficulty obtaining it.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 2 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 733 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

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