research DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy
Targeting ATM could help manage heart cell enlargement due to pressure overload.
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research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
research Long And Short Non-Coding RNA And Radiation Response: A Review
Non-coding RNAs could help detect and treat radiation damage.
research QS8: Analysis of the Whole Transcriptome in Breast Cancer Patients Undergoing Radiotherapy and Breast Reconstruction
Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.
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5 / 160 resultscommunity After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?
After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.
community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community Minoxidil works only with Retinoic acid
Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.
community Quit vaping/smoking = 80% less loss
Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
community How does dutasteride regrowth work?
A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.