Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

    September 2020 in “ Frontiers in Immunology ”
    Gantsetseg Tumurkhuu, Shuang Chen, Erica N. Montano … Moshe Arditi
    Studysummary In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.
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