Personalized Medicine in the Field of Inflammatory Skin Disorders

    March 2022 in “ Journal of Personalized Medicine ”
    Mircea Tampa, Monica Neagu, Constantin Căruntu, Simona Roxana Georgescu
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    Studysummary Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored. Our plain-language summary of this paper — not a Tressless recommendation.
    The document discusses the importance of personalized medicine in treating inflammatory skin disorders like psoriasis and atopic dermatitis. A study by Nicolescu et al. used a questionnaire to estimate psoriasis prevalence and risk factors in Romania, with a 99.13% match between questionnaire diagnosis and final diagnosis. Sobolev et al. found that low estrogen levels can influence psoriasis in women due to the differential expression of six estrogen-controlled genes. For atopic dermatitis treatment, Janus kinase inhibitors (JAK) are emerging as effective with tolerable side effects, as shown in a systematic review by Tsai et al. The document also explores novel biomarkers in connective tissue diseases, the connection between inflammation and skin tumors, and the role of cannabinoids in inflammation. A meta-analysis by Georgescu et al. found a significant positive correlation between the number of platelet-rich plasma treatments per month and the percentage change in hair density in patients with androgenic alopecia.
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