Intrinsic and Extrinsic Factors Associated with Hair Graying and Therapeutic Potential of Plant Extracts and Phytochemicals

August 2024 in “ Applied Sciences ”

Yong Chool Boo

hair graying canities oxidative stress genetic predispositions environmental influences melanocyte stem cells melanin synthesis Polygonum multiflorum Eriodictyon angustifolium phytochemicals plant extracts melanogenesis gray hair

TLDR Plant extracts may help prevent or reverse hair graying.

The review examines intrinsic and extrinsic factors contributing to hair graying, such as oxidative stress, genetic predispositions, and environmental influences, and evaluates the therapeutic potential of plant extracts and phytochemicals. Key findings include the role of melanocyte stem cells and the impact of oxidative stress and genetics on the graying process. Plant extracts like Polygonum multiflorum and Eriodictyon angustifolium show promise in reversing or preventing hair graying by enhancing melanin synthesis and reducing oxidative stress. Clinical trials and studies on animal models suggest these extracts can modulate key molecular pathways involved in melanogenesis, offering a natural therapeutic approach to mitigate hair graying.

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