Risk Factors for Premature Hair Graying in Young Turkish Adults

June 2016 in “ Pediatric Dermatology ”

Aslı Akin Belli, Fatma Etgü, Seyran Özbaş Gök, Bilge Kara, Gürsoy Doğan

premature hair graying PHG oxidative stress family history of PHG hair loss chronic disease perceived stress scale PSS

Studysummary This study found that premature hair graying in young Turkish men and women is associated with emotional stress, alcohol consumption, chronic diseases, and a family history of graying. Our plain-language summary of this paper — not a Tressless recommendation.

In a study of 1,119 young Turkish adults, 315 (28.1%) were found to have premature hair graying (PHG). The study, conducted between February and July 2015, identified that a higher prevalence of PHG was associated with factors such as family history of PHG, higher perceived stress scale (PSS) scores, alcohol consumption, presence of chronic disease, educational status, hair loss, age, and height. Multivariate analysis indicated that the severity of PHG was correlated with PSS score, age, hair loss, and family history of PHG. The findings suggest that PHG may be linked to oxidative stress in individuals who are genetically predisposed. The study's limitations include its exclusive focus on Turkish adults and possible recall bias regarding family history of PHG. Further research into the oxidative stress mechanisms involved in PHG was recommended.

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research Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study

46 citations , December 2014 in “Journal of The American Academy of Dermatology”

This study found that smoking, obesity, and family history are significant risk factors for premature hair graying in young men.

research Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors

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This study found that compromised antioxidant activity in gray hair follicles affects both mature melanocytes and their immature precursors, linked to down-regulation of melanogenesis-related genes.

research Premature Graying of Hair: Causes, Associations, and Treatments

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research Premature Hair Whitening Is an Independent Predictor of Carotid Intima-Media Thickness in Young and Middle-Aged Men

16 citations , January 2013 in “Internal Medicine”

This study found that premature hair whitening intensity is independently associated with increased carotid artery intima-media thickness, suggesting a link between hair whitening and cardiovascular risk.

research Premature Graying, Balding, And Low Bone Mineral Density In Older Women And Men

14 citations , April 2007 in “Journal of aging and health”

This study observed that balding was associated with lower total body BMD in men and higher hip BMD in women, possibly due to estrogen use in the latter group.

research Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage

210 citations , May 2006 in “The FASEB journal”

This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.