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GlossaryAndrogenetic Alopecia (PHG)

genetic hair loss influenced by androgens, often hereditary

Androgenetic Alopecia, commonly known as Male Pattern Baldness or Female Pattern Baldness, is a genetic condition characterized by progressive hair thinning and loss. It is influenced by androgens (male hormones) and typically follows a recognizable pattern, such as a receding hairline in men and diffuse thinning on the crown in women. This condition is the most common cause of hair loss, affecting both genders, and is often hereditary.

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research Increased PHGDH Expression Uncouples Hair Follicle Cycle Progression and Promotes Inappropriate Melanin Accumulation

1 citations , January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

Increased PHGDH expression causes early melanin buildup in hair follicles.

research Increased PHGDH Expression Promotes Aberrant Melanin Accumulation

January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)”

Higher PHGDH levels cause unusual melanin buildup in hair follicles.

research The Role of Phosphoglycerate Dehydrogenase in Cell Proliferation and Tumor Progression

January 2015 in “DSpace@MIT (Massachusetts Institute of Technology)”

PHGDH promotes cancer growth by aiding cell proliferation and tumor progression.

research Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study

46 citations , December 2014 in “Journal of The American Academy of Dermatology”

Premature hair graying in young men is linked to family history, obesity, and smoking.

research Risk Factors for Premature Hair Graying in Young Turkish Adults

26 citations , June 2016 in “Pediatric Dermatology”

Premature hair graying in young Turkish adults is more likely if they have stress, a family history of graying, drink alcohol, have chronic diseases, are older, or are taller.

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community SETIPIPRANT PGE2 GROUP BUY AND PIONEERING HAIR GROWTH

6 upvotes 9 years ago

The conversation is about a user seeking help with hair regrowth treatments, specifically mentioning Setipiprant, Minoxidil, Finasteride, and RU58841. The user is trying to contact forum members for guidance on making and using these treatments.

community Upcoming Setipiprant clinical trials hint at systemic daily dosage

23 upvotes 9 years ago

The conversation discusses the safety, tolerability, and efficacy of oral Setipiprant tablets for treating androgenetic alopecia compared to finasteride. It mentions the high cost of Setipiprant on the black market and the trial's end date in September 2017.

community The New, Improved CB-03-01/Setipiprant Group Buy

26 upvotes 9 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

community A reasonably reputable guy claims that he has reversed his hairloss. Could be an interesting read.

17 upvotes 10 years ago

A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.