1 citations
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January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a mouse model to mimic PHGDH gene copy number gain, finding that increased PHGDH expression leads to abnormal melanin production, which may offer insights into its role in melanoma.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” This study found that increased PHGDH expression in mice led to earlier melanin and melanocyte presence in hair follicles but did not induce cancer.
46 citations
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December 2014 in “Journal of The American Academy of Dermatology” This study found that smoking, obesity, and family history are significant risk factors for premature hair graying in young men.
26 citations
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June 2016 in “Pediatric Dermatology” This study found that premature hair graying in young Turkish men and women is associated with emotional stress, alcohol consumption, chronic diseases, and a family history of graying.
20 citations
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January 2016 in “International journal of trichology” In this study, premature hair graying in Indian patients under 25 was associated with low levels of serum ferritin, Vitamin B12, and high-density lipoprotein cholesterol.