Melanocyte Stem Cell Maintenance and Hair Graying

April 2005 in “ Cell ”

Eirı́kur Steingrı́msson, Neal G. Copeland, Nancy A. Jenkins

melanocyte stem cell hair graying Pax3 Mitf

TLDR Hair graying happens because certain cells aren't maintained properly.

Two recent papers from 2005 provided compelling evidence that hair graying was due to incomplete melanocyte stem cell maintenance. They identified Pax3 and Mitf as key molecules that regulated the balance between melanocyte stem cell maintenance and differentiation, shedding light on the underlying causes of hair graying as a sign of human aging.

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Melanocyte Stem Cell Maintenance and Hair Graying

Research cited in this study

research Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study

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