TLDR Acitretin treatment unexpectedly darkened a patient's gray hair.
A case report from April 2024 describes an unusual instance of hair repigmentation following the administration of acitretin, an oral retinoid typically associated with alopecia as a side effect. The patient experienced a darkening of hair color after undergoing treatment with acitretin, a phenomenon that is not well-documented in medical literature. This case highlights a potential, albeit rare, effect of acitretin on hair pigmentation.
Cited in this study
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2 citations
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January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
28 citations
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December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
31 citations
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April 2019 in “Journal of Cutaneous Pathology” Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
9 citations
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July 2016 in “The Journal of Dermatology” An 82-year-old man's white hair regained color after taking etretinate for psoriasis.
17 citations
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November 2013 in “Clinical and experimental dermatology” Acitretin therapy may cause hair to repigment and curl.