The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function

    August 2021 in “ EMBO Reports ”
    Anna Geueke, Giada Mantellato, Florian Kuester … Catherin Niemann
    Studysummary This study found that the anti-apoptotic Bcl-2 protein plays a crucial role in maintaining hair follicle stem cell function and influences tissue regeneration and tumor formation in mice.
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    Research cited in this study 16

    1. The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function EMBO Reports · 2021
    2. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer Trends in cell biology · 2018
    3. The Dynamic Duo: Niche and Stem Cell Interdependency Stem Cell Reports · 2015
    4. Stem Cell Heterogeneity and Plasticity in Epithelia Cell Stem Cell · 2015
    5. Stem Cell Dynamics in the Hair Follicle Niche Seminars in Cell & Developmental Biology · 2013
    6. Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop Genes & Development · 2012
    7. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    8. TCF/Lef1 Activity Controls Establishment of Diverse Stem and Progenitor Cell Compartments in Mouse Epidermis The EMBO Journal · 2011
    9. Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development Birth defects research · 2009
    10. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    11. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    12. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    13. Hair Follicle Stem Cells: Insights from the 2003 Workshop ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    14. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    15. Hair Follicle Apoptosis And Bcl-2 Journal of Investigative Dermatology Symposium Proceedings · 1999
    16. The Biology of Hair Follicles The New England Journal of Medicine · 1999

    Related research 2

    1. Keratins of the Human Hair Follicle International review of cytology · 2005
    2. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001