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GlossaryB-cell lymphoma 2 (Bcl-2 protein)

protein that inhibits cell death, often overexpressed in cancers

B-cell lymphoma 2 (Bcl-2) is a protein that helps regulate cell death (apoptosis) by inhibiting the process, allowing cells to survive longer than they should. This protein is often overexpressed in certain types of cancer, such as lymphomas, making it a target for cancer therapies aimed at restoring the normal process of cell death.

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research Research Paper: Effects of Sandalwood and Rose Absolute Oils on Hair Growth

January 2008 in “한국미용학회지”

Sandalwood and rose absolute oils can help hair regrow faster.

research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells

58 citations , January 2006 in “Skin Pharmacology and Physiology”

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Hair Growth-Promoting Activity of Citron Seed Oil: Induction of Premature Telogen-To-Anagen Transition of Hair Follicle in C57BL/6 Mouse Models

research Hair Growth-Promoting Activity of Citron Seed Oil: Induction of Premature Telogen-To-Anagen Transition of Hair Follicle in C57BL/6 Mouse Models

April 2021 in “Current Topics in Nutraceutical Research”

Citron seed oil may help prevent or treat hair loss by promoting hair growth and increasing hair density.

research Effects of Diphencyprone on Expression of Bcl-2 Protein in Patients with Alopecia Areata

13 citations , January 2010 in “Immunopharmacology and immunotoxicology”

Diphencyprone increases Bcl-2 protein in patients with hair regrowth from alopecia areata.

research Topical Botanical Extract for Management of Chemotherapy-Induced Alopecia

March 2014 in “Journal of The American Academy of Dermatology”

A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.

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community The end of balding: We may have just found the secret to hair regrowth

in Technology 680 upvotes 11 months ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.

community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

in Research/Science 4 upvotes 3 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

in Update 17 upvotes 4 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.