74 citations,
January 2013 in “Expert Opinion on Biological Therapy”
The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stemcell technology.
72 citations,
July 2012 in “Journal of Investigative Dermatology”
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stemcells necessary for hair growth, leading to progressive hair loss.
Microneedling stimulates hair growth through stemcellactivation during wound healing, not just increased blood flow. Other methods like showers or supplements don't replicate this effect.
User hoodoomoovoo discusses their interest in stemcell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stemcells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.