Hair Aging And Anti-Aging

The document from 2007 explores the phenomenon of hair aging, including changes in the hair shaft and follicle that lead to graying and decreased hair production, as seen in androgenetic and senescent alopecia. It reviews the esthetic and biological aspects of aging hair, the impact of intrinsic and extrinsic factors like genetics, UV radiation, and smoking, and current treatments such as minoxidil, finasteride, and hair transplantation. The paper also discusses the psychological effects of hair loss, the role of DHT and androgen receptors in AGA, and the need for further research and public health education. It highlights the importance of scalp sun protection and the use of antioxidants, and notes the varying effectiveness of treatments like finasteride and minoxidil, especially in women. Additionally, 38% of patients at the Palm Springs Life Extension Institute saw improvements in hair thickness and structure with recombinant human growth hormone treatment. The document emphasizes the potential of tissue engineering and targeted delivery of active compounds to hair follicles, despite existing challenges. It references several clinical trials and studies on the efficacy of minoxidil and finasteride in treating patterned hair loss but does not specify the number of participants in these studies.