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Glossary Growth Hormone

peptide hormone from the pituitary gland that stimulates growth

Growth Hormone (GH), also known as Human Growth Hormone (HGH) or somatotropin, is a peptide hormone produced by the pituitary gland. It plays a crucial role in growth, cell repair, and metabolism by stimulating the liver to produce another hormone called insulin-like growth factor 1 (IGF-1), which promotes the growth of bones and tissues. GH is also involved in regulating body composition, muscle and bone growth, and overall physical performance.

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Research

5 / 1000+ results

research Dermal Changes in Osteoporosis Following Prolonged Treatment with Human Growth Hormone

9 citations , October 1976 in “Journal of Cutaneous Pathology”

This study observed that human growth hormone treatment in osteoporosis patients appeared to improve skin thickness and restore dermal structures towards normal without stimulating hair, sebum, or melanin.

Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density

research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Micro Vessel Density

January 2024

In this animal study, rats treated with recombinant human growth hormone (at both low and high doses) experienced quicker burn wound healing than controls, with increased micro vessel density and altered expression of vascular endothelial growth factor, alongside changes in oxidative stress and inflammation markers.

research Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo

8 citations , January 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review discusses how neuroendocrine regulation affects human hair follicles and suggests potential therapeutic targets, but it reports no new clinical results.

research Topically applied thyroid hormones stimulate hair growth in organ-cultured human scalp skin

June 2024

This study suggests that topically applied thyroid hormones T3 and T4 promote hair growth on human scalp tissues ex vivo, highlighting potential therapeutic use for hair loss conditions like androgenetic alopecia.

research Growth Hormone and the Human Hair Follicle

14 citations , December 2021 in “International journal of molecular sciences”

This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.

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Community Join

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community Why does the same hormone grow your beard and destroy your hairline?

44 upvotes 4 months ago

DHT promotes beard growth but causes scalp hair loss due to inflammation and fibrosis. Treatments like finasteride and minoxidil help with hormonal signals and blood flow but don't address underlying inflammation.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

24 upvotes 1 year ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

community The use of peptides to enhance hair growth from wounding

4 upvotes 9 years ago

The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

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Learn

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learn sh-Polypeptide-7

How does sh-Polypeptide-7 help stimulate hair follicle activity or reduce scalp inflammation? sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.

learn Stem Cell Factor

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Latanoprost

How long does it usually take to see results from latanoprost for hair growth? There is no established timeline: the only human scalp trial, a 16-man pilot, measured a hair-density increase at 24 weeks using latanoprost 0.1% — twenty times the strength of the glaucoma eye drop — and faster figures quoted elsewhere come from eyelash and animal observations. Scalp use is off-label and experimental.

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

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