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    Glossary Senescent Alopecia

    gradual hair thinning due to aging of hair follicles

    Senescent Alopecia, also known as Age-Related Hair Loss, refers to the gradual thinning and loss of hair that occurs as a natural part of the aging process. Unlike androgenetic alopecia, which is influenced by genetic and hormonal factors, senescent alopecia is primarily due to the aging of hair follicles, leading to a reduction in hair density and diameter over time.

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      community The Real Cause Of Androgenetic Alopecia

       675 upvotes 1 year ago
      Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

      community The mechanism of androgenic alopecia

       36 upvotes 11 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community I wish I were a man so bad. Life is cruel

       225 upvotes 6 months ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss