My personal experience/observations fighting AGA seriously for 5 years
    12/7/2024

    From the encyclopedia
    Minoxidil →

    Vasodilator used on the scalp and, at low doses, as a tablet

    RU58841 →

    Experimental topical anti-androgen sold as a research chemical

    Finasteride →

    Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

    At a glance
    In this treatment experience post, the primary subjects mentioned are
    💧 Minoxidil (topical) 10% 2x daily 5 years
    💧 RU58841 (topical) 2.5% solution 1x daily
    💊 Finasteride (oral) 1mg 1x daily 1.5 years
    💧 Finasteride (topical) 0.1% 2x daily
    💧 Tretinoin (topical) 2 months
    💧 Ketoconazole (topical) 2% daily
    💧 Pyrilutamide (topical) 0.5%/1% 1x daily 3 months
    💧 Eucapil (topical)
    • Microneedling fortnightly
    • PRP
    the tone is 😐 neutral with mixed results.

    Other terms

    Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.
    View this post in the Community →

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    Related research 6

    1. Compounding as a Current Therapeutic Option in Dermatology Actas Dermo-Sifiliográficas · 2013 · 1 citations
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    3. Polystyrene-b-poly (acrylic acid) nanovesicles coated by modified chitosans for encapsulation of minoxidil Brazilian Journal of Pharmaceutical Sciences · 2022 · 1 citations
    4. Current Advances of Nanocarrier Technology-Based Active Cosmetic Ingredients for Beauty Applications Clinical, Cosmetic and Investigational Dermatology · 2021 · 33 citations
    5. New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice International Journal of Pharmaceutics · 2000 · 37 citations
    6. Novel prospectives of shikimic acid and Prunus mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment Frontiers in Natural Products · 2026