A Clinical Study of Premature Graying and Its Association with Hemoglobin, Ferritin, and Calcium Levels

    Sruthi Chandran, Sheena Ann Simon, Anuja Elizabeth George
    TLDR Low ferritin and high Anti TPO levels are linked to early hair greying.
    This study investigated the association between premature hair greying (PHG) and levels of hemoglobin, ferritin, and calcium in a sample of 40 patients compared to 40 controls. The study found that low serum ferritin and raised Anti Thyroid Peroxidase (Anti TPO) levels were significantly associated with PHG. The mean age of patients was 17.14 years, with a slight male predominance and a common onset of greying between 16 and 20 years. A positive family history, particularly paternal, was noted, and the vertex was the most common site of onset. The findings suggested that low ferritin and elevated Anti TPO levels might play a role in the development of premature canities.
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