16 citations
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January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that premature hair graying is strongly associated with a family history, Vitamin B12 deficiency, and hypothyroidism, with onset as early as 5 years in patients in Gurugram, India.
15 citations
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January 2017 in “Pigment International” This article reviews the pathogenesis and treatment approaches for premature graying of hair, noting the unsatisfactory options currently available, and reports no new clinical findings.
7 citations
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June 2020 in “Experimental dermatology” This study identified key lipid differences between black and white hair in individuals with premature greying, highlighting vitamin D3 as a potential target for further research in understanding this condition.
7 citations
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January 2016 in “Hair therapy & transplantation” This study reported significantly lower levels of serum iron, ferritin, and calcium in young patients with premature gray hair compared to controls, implying that supplementation might prevent further graying.
3 citations
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May 2022 in “Indian Journal of Dermatology” This study found that premature hair greying may be associated with low serum ferritin and raised anti-TPO levels.