Three Streams for the Mechanism of Hair Graying

    January 2018 in “ Annals of dermatology/Annals of Dermatology ”
    Seong Kyeong Jo, Ji Yeon Lee, Young Lee … Jeung‐Hoon Lee
    Studysummary This review examines current understanding of hair graying and suggests it may be caused by depletion of melanocyte stem cells due to genotoxic stress or dysfunctional melanocytes from oxidative stress.
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    Research cited in this study 19

    1. Factors Associated With Premature Hair Graying in a Young Indian Population International journal of trichology · 2016
    2. Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study Journal of The American Academy of Dermatology · 2014
    3. Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress International Journal of Cosmetic Science · 2013
    4. B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance Cell Reports · 2012
    5. Hair Greying Is Associated With Active Hair Growth British Journal of Dermatology · 2011
    6. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    7. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011
    8. A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation Pigment Cell & Melanoma Research · 2010
    9. Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role? Journal of Investigative Dermatology · 2009
    10. Senile Hair Graying: H2O2-Mediated Oxidative Stress Affects Human Hair Color by Blunting Methionine Sulfoxide Repair The FASEB Journal · 2009
    11. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    12. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    13. Towards A Free Radical Theory Of Graying: Melanocyte Apoptosis In The Aging Human Hair Follicle As An Indicator Of Oxidative Stress Induced Tissue Damage ˜The œFASEB journal · 2006
    14. Hair Melanocytes as Neuro-Endocrine Sensors—Pigments for Our Imagination Molecular and cellular endocrinology · 2005
    15. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    16. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    17. Characterization of Human Keratin-Associated Protein 1 Family Members ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    18. Keratinocyte Growth Factor Is an Important Endogenous Mediator of Hair Follicle Growth, Development, and Differentiation. Normalization of the Nu/Nu Follicular Differentiation Defect and Amelioration of Chemotherapy-Induced Alopecia. PubMed · 1995
    19. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993

    Related research 6

    1. Hair Loss (Alopecia or Baldness) 2018
    2. Treatments of Hereditary Hair Loss (Alopecia) 2018
    3. Female Patients Complaining About Hair Loss: Documentation of Defective Scalp Hair Dynamics with Contrast-Enhanced Phototrichogram Skin Research and Technology · 2006
    4. Treatment of Hair Loss The New England Journal of Medicine · 1999
    5. Clinical Updates in Hair Dermatologic Clinics · 1997
    6. Disorders of Hair Growth: Diagnosis and Treatment McGraw-Hill eBooks · 1994