Search

for
Search:

Glossary UV-induced DNA damage

harm to DNA caused by ultraviolet radiation

UV-induced DNA damage refers to the harm caused to DNA by ultraviolet (UV) radiation from sources like the sun. This damage can result in mutations, such as thymine dimers, where two adjacent thymine bases bond together, disrupting normal DNA replication and potentially leading to skin cancers and other genetic disorders.

Related Terms

Research

5 / 1000+ results

research In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis

10 citations , June 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, researchers found that the vitamin D receptor plays a crucial role in promoting differentiation and protecting against UVB-induced DNA damage in murine melanocytes, suggesting potential implications for melanoma progression.

research Editor's evaluation: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

June 2021

This study found that UV radiation-induced fibroblast depletion in the skin is primarily due to a deregulated inflammatory response, with T cells aiding fibroblast survival under stress.

Transepidermal UV Radiation of Human Scalp Skin Induces Distinctive Hair Follicle Damage, Mitigated by Topical Caffeine Treatment

research 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment

April 2019 in “Journal of Investigative Dermatology”

This study found that ultraviolet radiation causes significant damage to human hair follicles, including increased cell apoptosis and oxidative DNA damage, but this damage may be mitigated by topical caffeine.

Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine

research Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine

31 citations , February 2019 in “International Journal of Cosmetic Science”

This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.

research Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage

1 citations , June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that fibroblast loss in the upper dermis from UVR exposure is linked to a deregulated inflammatory response, with T cells playing a protective role in fibroblast survival.

View more "uv-induced dna damage" in research →

Community Join

3 / 1000+ results

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 64 upvotes 2 years ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Has anyone powered through the creatine shedding (via increased androgen receptor sensitivity) and stabilized?

9 upvotes 1 year ago

Creatine may cause increased hair shedding due to androgen receptor sensitivity, despite limited evidence. The user is using dutasteride and minoxidil and seeks advice on whether shedding will stabilize, with suggestions including GHK-Cu and RU58841.

View more "uv-induced dna damage" in community →

Clinics

6 / 13 results

All 13 clinic results →

Learn

— no results

Try a deeper search in learn →

Experts

— no results

Try a deeper search in experts →