Editor's Evaluation: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage

June 2021

Edward E Morrisey

ultraviolet radiation UVR fibroblasts immune cells collagen neutrophils T cell subpopulations pro-inflammatory prostaglandin signaling CD4-positive cells CD8-positive cells DNA damage pro-inflammatory prostaglandins fibroblast proliferation papillary fibroblasts extracellular matrix inflammatory response infiltrating T cells COX-2 prostaglandin synthesis neutrophil infiltration UV radiation T cells prostaglandins COX-2 enzyme

Studysummary This study found that UV radiation-induced fibroblast depletion in the skin is primarily due to a deregulated inflammatory response, with T cells aiding fibroblast survival under stress.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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