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GlossaryMutagenesis

process of inducing genetic mutations in an organism's DNA

Mutagenesis is the process by which the genetic information of an organism is changed, resulting in a mutation. This can occur naturally, such as through errors in DNA replication, or be induced by external factors like radiation or chemicals. For professionals, understanding mutagenesis is crucial for fields like genetics, cancer research, and evolutionary biology, as it underpins the mechanisms of genetic variation and disease.

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research Rand Protease: The Role of Calcium-Binding Site on Stability with Mutagenesis and The Effectiveness on Leather Dehairing

December 2023 in “Sains Malaysiana”

The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.

research Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis

9 citations , January 2011 in “EXPERIMENTAL ANIMALS”

A new rat strain with a specific gene mutation causes hair loss and kidney issues.

research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas

5 citations , June 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.

research A Novel Missense Mutation in the Mouse Hairless Gene Causes Irreversible Hair Loss: Genetic and Molecular Analyses of Hrm1Enu

18 citations , February 2006 in “Genomics”

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

research PNKP Is Required for Maintaining the Integrity of Progenitor Cell Populations in Adult Mice

3 citations , July 2021 in “Life science alliance”

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

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