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cellular mechanisms detect and repair damaged DNA to maintain integrity

The DNA damage response (DDR) is a complex network of cellular processes that detect and repair damage to the DNA, ensuring the integrity of the genetic material. When DNA is damaged by factors like UV radiation or chemicals, DDR mechanisms activate to either fix the damage or, if repair is not possible, trigger cell death to prevent the propagation of faulty DNA. This system is crucial for preventing mutations that could lead to diseases such as cancer.

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