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    Glossary BRCA2

    gene involved in DNA repair and cancer risk

    BRCA2 is a gene that produces a protein responsible for repairing damaged DNA, playing a crucial role in maintaining the genetic stability of cells. Mutations in the BRCA2 gene can lead to an increased risk of developing certain cancers, most notably breast and ovarian cancer, as the impaired DNA repair mechanism allows for the accumulation of genetic errors.

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    Research 10 of 204

    1. BRCA2 in abscission Nature Cell Biology · 2012
    2. Commentary on BRCA1-Associated Protein-1 Tumor Predisposition Syndrome in a Patient With Numerous Basal Cell Carcinomas Dermatologic Surgery · 2019
    3. Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1 Molecular and Cellular Biology · 2004 · 48 citations
    4. One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions The Milbank Quarterly · 2005 · 35 citations
    5. Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women Human Reproduction · 2006 · 25 citations
    6. Rare Germline Pathogenic Variants Identified by Multigene Panel Testing and the Risk of Aggressive Prostate Cancer Cancers · 2021 · 20 citations
    7. CPC12 Coinheritance of <i>BRCA2</i> and <i>CYLD</i> germline pathogenic variants associated with targetable metastatic malignant cylindroma British Journal of Dermatology · 2023
    8. Case Study: Hereditary Cancer Genetic Testing in Unaffected Patients May Allow for Early Intervention and Aggressive Management Journal of Minimally Invasive Gynecology · 2014
    9. Ductal breast cancer in a male patient International Journal of Dermatology · 2010
    10. HRT for women with premature ovarian insufficiency: a comprehensive review Human Reproduction Open · 2017 · 61 citations
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