Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
January 2013
in “
The journal of investigative dermatology/Journal of investigative dermatology
”
human induced pluripotent stem cells ectodermal precursor cells hair follicle morphogenesis hair follicle hiPSC-EPCs human dermal papilla cells follicular keratinocyte markers WNT-activated state trichogenic mice dermal cells immunodeficient mice epithelial-mesenchymal interactions HF bioengineering hiPSCs DP cells WNT signaling hair follicle formation hair growth
Studysummary This study found that ectodermal precursor cells derived from human induced pluripotent stem cells may enhance hair follicle morphogenesis through improved epithelial-mesenchymal interactions when cocultured with dermal cells.
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