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    Glossary Immunodeficient Mice

    laboratory mice with weakened or absent immune systems

    Immunodeficient mice, also known as immunocompromised mice, are laboratory mice that have a weakened or entirely absent immune system. This makes them valuable for scientific research, particularly in studying human diseases, cancer, and testing new treatments, as they can accept human cells and tissues without rejecting them.

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    1. Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice Journal of The American Academy of Dermatology · 2003 · 17 citations
    2. A novel hairless highly immunodeficient mice model optimized for in vivo imaging Laboratory Animal Research · 2026
    3. Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice Journal of Investigative Dermatology · 2000 · 31 citations
    4. A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype ˜The œAmerican journal of pathology · 2014 · 11 citations
    5. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts 1998 · 131 citations
    6. Follicles Twisted During Follicular Unit Excision Could Survive in the Skin of Nude Mice Dermatologic Surgery · 2025
    7. 080 Mouse models of alopecia areata: C3H/HeJ mice versus the humanized AA mouse model Journal of Investigative Dermatology · 2019
    8. Tissue engineering of human hair follicles using a biomimetic developmental approach Nature Communications · 2018 · 184 citations
    9. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    10. MOUSE MODELS FOR THE STUDY OF HUMAN HAIR LOSS Dermatologic Clinics · 1996 · 36 citations
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