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Glossary HIV-2

virus causing a less common, slower-progressing HIV infection

HIV-2, or Human Immunodeficiency Virus Type 2, is a virus that causes a form of HIV infection, similar to but less common and generally less aggressive than HIV-1. It is primarily found in West Africa and is characterized by a slower progression to AIDS and lower transmission rates compared to HIV-1.

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Research

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research Bibliometric analysis and visualization of research trends on HIV-1 capsid inhibitors (2000–2022)

October 2023 in “Frontiers in Pharmacology”

In this bibliometric study, researchers analyzed 96 publications from 2000 to 2022 to identify trends in HIV-1 capsid inhibitor research, highlighting the USA as a leading contributor and emphasizing the importance of molecular studies and drug discovery in advancing antiretroviral therapy.

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

This research reported that STAT5 activation in the dermal papilla plays a crucial role in triggering anagen entry during post-developmental hair follicle cycling.

research 264 CCR5 blockade shows prevention of alopecia areata development as well as improvement of alopecia areata

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that orally administering the CCR5 inhibitor Maraviroc improved hair loss in 4 out of 5 mice with alopecia areata and also reduced the development of the condition, evidenced by decreased CCR5+ T-cell infiltration in treated mice.

Chemokine Receptor CCR5 as a Novel Target for the Treatment of Alopecia Areata

research 218 Chemokine receptor CCR5 is the novel target for the treatment of alopecia areata

August 2016 in “Journal of Investigative Dermatology”

This study reported improvement in hair loss lesions in C3H/HeJ mice with alopecia areata following treatment with the CCR5 inhibitor maraviroc, alongside reduced infiltration of specific T cells in the lesions.

research Electron microscopy in dermatology--basic and clinical research : proceedings of the Joint Meeting for the Japanese Society for Ultrastructural Cutaneous Biology and the Society for Cutaneous Ultrastructure Research, Nara, Japan, 24-27 October 1993

January 1994 in “Medical Entomology and Zoology”

This article reviews various microscopy techniques and their applications in dermatology but reports no new experimental results.

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Clinics

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community My experience with finasteride and outlook on hairloss

13 upvotes 5 years ago

The user started finasteride at 21.5 years old and saw significant improvement in hair volume and maintenance of the hairline, though some recession continued. They are optimistic about future hair loss treatments like CRISPR and are not currently using additional treatments like minoxidil or derma-rolling.

community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

371 upvotes 8 months ago

Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.

community There is simply no way to get finasteride in Germany

in Finasteride/Dutasteride 82 upvotes 2 years ago

A user in Germany struggles to get a finasteride prescription despite trying multiple doctors and apps, only receiving minoxidil. Other users suggest alternative sources like Zava.med, EU doctor App, and buying from pharmacies abroad.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

112 upvotes 1 year ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

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