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Glossary HIV entry inhibitor

prevents HIV from entering and infecting immune cells

An HIV entry inhibitor is a type of antiretroviral drug that prevents the HIV virus from entering human immune cells, specifically CD4+ T cells. By blocking the virus's ability to fuse with the cell membrane, these inhibitors stop the infection process at an early stage, thereby reducing the viral load in the body and helping to manage HIV infection.

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research 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

This research reported that STAT5 activation in the dermal papilla plays a crucial role in triggering anagen entry during post-developmental hair follicle cycling.

research [Study of gonadal hormone drugs in blocking filovirus entry of cells in vitro].

5 citations , December 2015 in “PubMed”

This study identified several gonadal hormone drugs, including toremifene citrate, tamoxifen citrate, and clomiphene citrate, that effectively inhibited filovirus entry in a pseudovirus model.

research Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight

21 citations , December 2022 in “Biomolecules”

This review explores the potential of isoquinoline and related alkaloids in combating viral infections by examining their mechanisms of action and drug discovery applications, but reports no new clinical results.

research Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

70 citations , July 2020 in “Pharmacological Reports”

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

research 218 Chemokine receptor CCR5 is the novel target for the treatment of alopecia areata

August 2016 in “Journal of Investigative Dermatology”

This study reported improvement in hair loss lesions in C3H/HeJ mice with alopecia areata following treatment with the CCR5 inhibitor maraviroc, alongside reduced infiltration of specific T cells in the lesions.

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