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    GlossaryInduced Pluripotent Stem Cells

    cells reprogrammed from adult cells to an embryonic-like state

    Induced Pluripotent Stem Cells (iPSCs) are a type of stem cell that scientists create by reprogramming adult cells, such as skin or blood cells, to revert to an embryonic-like state. This process allows these cells to potentially develop into any type of cell in the body, making them valuable for research, regenerative medicine, and disease modeling.

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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

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      community Please explain this Minoxidil phenomena

      in Minoxidil  56 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  142 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  743 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.