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    Glossary Telomerase

    enzyme that extends chromosome ends to prevent shortening

    Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes, known as telomeres, to prevent them from becoming too short during cell division. This process is crucial for maintaining the stability and integrity of genetic information, particularly in stem cells and cancer cells, which divide frequently.

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    Research 10 of 574

    1. Conditional telomerase induction causes proliferation of hair follicle stem cells Nature · 2005 · 414 citations
    2. Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice Aging Cell · 2016 · 30 citations
    3. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    4. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021 · 12 citations
    5. Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease Journal of Cutaneous Pathology · 2000 · 11 citations
    6. Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita Science Advances · 2025 · 3 citations
    7. Immunolocalization of telomerases in human hairs identifies proliferating cells in the bulb matrix and outer root sheath 2024
    8. Stem and cancer cells Wnt long telomeres Nature Cell Biology · 2012
    9. Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2005
    10. The Telomerase Reverse Transcriptase (TERT) Gene Molecular Characterization in Sheep and the Association of Its Variation with Wool Traits Animals · 2026
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