Mesenchymal Stem Cell Therapy for Skin Repair and Rejuvenation

    June 2026 in “ Discover Immunity. ”
    Irene Raitman, Lin Kang, Anna Gosiewska … Robert Hariri
    Studysummary This review discusses current advancements in mesenchymal stem cell-based therapies for skin repair and rejuvenation, focusing on therapeutic strategies, particularly highlighting the potential of neonatal and placenta-derived MSCs, and reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Synergistic Effects of Mesenchymal Stem Cells and Their Secretomes with Scaffolds in Burn Wound Healing: A Systematic Review and Meta-Analysis of Preclinical Studies Journal of Translational Medicine · 2025
    2. Exploring the Dermatological Applications of Human Mesenchymal Stem Cell Secretome: A Comprehensive Review Stem Cell Research & Therapy · 2025
    3. Effects of Hydrogels on Mesenchymal Stem/Stromal Cells Paracrine Activity and Extracellular Vesicles Production Journal of Extracellular Vesicles · 2025
    4. Role of Umbilical Cord Mesenchymal Stromal Cells in Skin Rejuvenation npj Regenerative Medicine · 2024
    5. The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration Biomedicines · 2024
    6. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021
    7. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging International Journal of Molecular Sciences · 2017
    8. Mechanisms Regulating Skin Immunity and Inflammation Nature Reviews Immunology · 2014