TLDR Mesenchymal stem cells show promise for effective skin repair and regeneration.
Mesenchymal stem cells (MSCs) show significant promise in skin repair and regeneration by promoting wound healing through mechanisms like neovascularization, immunomodulation, and paracrine signaling. Derived from sources such as human umbilical cord, bone marrow, and adipose tissue, MSCs can accelerate wound closure, reduce scar formation, and enhance collagen production. Advanced delivery methods, including hydrogels and scaffolds, further improve their therapeutic effects. Despite promising preclinical and clinical results, challenges like cell quality control and immunological rejection remain, necessitating further research to optimize MSC-based therapies for widespread clinical use.
1 citations,
August 2023 in “Military Medical Research” Smart hydrogel dressings could improve diabetic wound healing by adjusting to wound conditions and controlling drug release.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
48 citations,
July 2019 in “International Journal of Biological Macromolecules” A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
23 citations,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
10 citations,
July 2011 in “Wound Repair and Regeneration” New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
1 citations,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
