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    Glossary Paracrine Signaling

    cells communicate by releasing molecules to nearby cells

    Paracrine signaling is a form of cell-to-cell communication where a cell produces signaling molecules, such as growth factors or cytokines, that affect nearby target cells within the same tissue. Unlike endocrine signaling, which involves hormones traveling through the bloodstream to distant targets, paracrine signals act locally, ensuring a rapid and specific response in the immediate cellular environment. This type of signaling is crucial in processes like wound healing, immune responses, and hair follicle regulation.

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    1. Androgen Receptor–Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia Journal of Investigative Dermatology · 2022 · 6 citations
    2. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012 · 321 citations
    3. Human CD133 <sup>+</sup> Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling Circulation Research · 2009 · 245 citations
    4. Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages Nature Communications · 2016 · 115 citations
    5. Cx43 hemichannel-mediated paracrine involves in the promotion of MSCs on skin wound healing Stem Cell Research & Therapy · 2025 · 1 citations
    6. Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 1 citations
    7. Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla Journal of Dermatological Science · 2010 · 122 citations
    8. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice* Endocrinology · 2001 · 73 citations
    9. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001 · 14 citations
    10. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations
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