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    GlossaryParacrine Factors

    signaling molecules affecting nearby cells within same tissue

    Paracrine factors are signaling molecules that are released by cells and affect nearby target cells within the same tissue. Unlike hormones that travel through the bloodstream to distant sites, paracrine factors act locally to regulate processes such as cell growth, differentiation, and immune responses. For example, in the context of hair growth, paracrine factors can influence the behavior of hair follicle cells, potentially impacting conditions like alopecia.

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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  733 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 3 weeks ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community Just had this wild thought come into my head.

      in Satire  403 upvotes 1 year ago
      The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.