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    GlossaryParacrine Factors

    signaling molecules affecting nearby cells within same tissue

    Paracrine factors are signaling molecules that are released by cells and affect nearby target cells within the same tissue. Unlike hormones that travel through the bloodstream to distant sites, paracrine factors act locally to regulate processes such as cell growth, differentiation, and immune responses. For example, in the context of hair growth, paracrine factors can influence the behavior of hair follicle cells, potentially impacting conditions like alopecia.

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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community One year off fin/min and I regret it

      in Update  383 upvotes 3 days ago
      The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.